PAA in Healthcare

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Peracetic Acid in the healthcare industry.

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1. Steri-Trac ® Peracetic Acid Monitor “Protecting What Matters Most” Peracetic acid (PAA) is an ideal antimicrobial agent due to its high oxidizing potential. PAA is used for high level disinfection and sterilization in healthcare facilities. Unfortunately, PAA is commonly used in concentrations harmful to employees if exposed. ChemDAQ is the leader in environmental monitoring of antimicrobial agents and disinfectants like PAA. Given the known health affects from exposure to PAA, the EPA has established exposure limits based on the toxicity to humans and OSHA / ACGIH have established exposure limits for its’ two ingredients, hydrogen peroxide and acetic acid. Continuous environmental monitoring protects employees from acute and chronic health affects by recording the toxic concentrations in real time and providing alerts for proactive protection. A continuous monitoring system coupled with safe work practices and a comprehensive education program are the best ways to assure employee safety and maximize productivity. At ChemDAQ, we are committed to helping you protect what matters most. DAQ ® Central Monitoring System ChemDAQ’s DAQ ® Central Monitoring System is a PC-Based data acquisition and management system. Steri-Trac Area Monitors are complete, stand-alone gas monitoring instruments and the DAQ is an integral part of a multi-point, multi-gas system. The DAQ provides features like real time tracking and display of time weighted averages (TWA) such as the OSHA PEL. The DAQ provides a centralized view of the entire system, including automatic record keeping and advanced reporting capability. Finally, the Steri-Trac’s modular design makes it easy to custom configure an installation to meet each facility's specific needs. The Steri-Trac PAA Area Monitor displays real-time PPM concentrations and annunciates alarms when exposure levels reach pre-set levels. Large tri-color LED display with 2 user-defined alarm thresholds:  Low alarm results in a flashing yellow display and pulsing alarm horn.  High alarm results in a flashing red display and continuous alarm horn. Our exclusive Sensor Calibration/Exchange Program (SXP®) — part of ChemDAQ’s sensor usage agreement — virtually eliminates maintenance by providing factory calibrated PAA sensors to clients at regular intervals. Steri-Trac ® Area Monitors Overview

2. Peracetic Acid Summary of Health Hazards Sterilant Gas Exposure Limits Health Hazards Peracetic Acid (PAA) Common Uses: disinfection and high level sterilization for hospitals and healthcare facilities, hard surface sanitizing, waste water disinfection, sanitize conveyors and belts (food contact), food utensils, tableware, bottle rinse, pulp and paper, pasteurizers, air washers, fruit and vegetable wash, irrigation and drip systems, etc. Acute Exposure Guideline Levels (EPA) 1,3 (page 28) AEGL 1: 0.17 ppm, 10 min to 8 hrs AEGL 2: 0.5 ppm, 10 min to 8 hrs AEGL 3: 19.3 ppm, 10 min to 1.3 ppm, 8 hrs PAA mixture contains PAA, hydrogen peroxide and acetic acid. Although the combination of acetic acid and hydrogen peroxide contribute to the toxicity of the PAA mixture, PAA is the most toxic agent of the three. OSHA PELs (8Hr TWA) 2 Hydrogen Peroxide: 1ppm Acetic Acid: 10ppm SOLVAY EEIs 3 (page 29) EEI 1: 0.15ppm EEI 2: 3ppm EEI 3: 50ppm Primary Irritant 4 Known Tumorigen 5 Possible Animal Carcinogen 6  Severe irritation and burning of the skin and eyes leading to eye damage, irritation of the nose and throat, irritation of the lungs causing coughing and/or shortness of breath 7 .  Higher exposures can cause pulmonary edema, liver and kidney affects 8 .  Epigastric pain which may be associated with nausea and vomiting, gastric hemorrhage, ulceration of membranes and tissues, circulatory collapse with clammy skin, weak and rapid pulse, shallow respiration, and scanty urine 9 .  Late esophageal, gastric, and pyloric strictures and stenoses which may not appear until months or years later 10 .  Permanent scarring of the cornea, skin, and oropharynx 11 .  Uncorrected circulatory collapse could lead to renal failure and ischemic lesions in liver and heart 12 . 1 Environmental Protection Agency , http://www.epa.gov/oppt/aegl/pubs/results80.htm 2 Occupational Safety and Health Administration , http://www.osha.gov/SLTC/healthguidelines/hydrogenperoxide/recognition.html & http://www.osha.gov/pls/oshaweb/owadisp.show_document?p_table=standards&p_id=9992 3 Environmental Protection Agency , http://www.epa.gov/oppt/aegl/pubs/peraceticacid_interim_ornl_jun2008%20_c.pdf SOLVAY (1998) (Belgium manufacturer of peracetic acid) derived Emergency Exposure Indices (EEI) for accidental releases of peracetic acid based on the methodology of the European Chemical Industry Ecology and Toxicology Centre (ECETOC). These values are derive d for general population exposures. The values are as follows:  SLV-EEI-3 (death/permanent incapacity): the threshold above which mortality and/or irreversible effects could be observed for a n exposure of up to 60 minutes.  SLV-EEI-2 (disability): the threshold level above which intense lacrimation, extreme nose discomfort and transient incapacitati on (inability of self protection but without residual consequences) could be observed for an exposure of up to 60 minutes.  SLV-EEI-1 (discomfort): the threshold level above which discomfort could be observed for an exposure of up to 8 hours per day. 4,5 National Institute for Occupational Safety and Health , http://www.skcgulfcoast.com/nioshdbs/rtecs/sd8583b0.htm 6,7,8 New Jersey Dept. of Health and Senior Services , http://nj.gov/health/eoh/rtkweb/documents/fs/1482.pdf 9,10.11,12 United States National Library of Medicine: Toxicology Data Network , http://toxnet.nlm.nih.gov/cgi-bin/sis/search

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